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Sacubitril-d4 21718 Epub 2015 Dec 7

SKU: 26266506222

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Description

Epub 2015 Dec 7

(2013) Proc Natl Acad Sci U S A

Targeting RNA structure in SMN2 reverses spinal muscular atrophy molecular phenotypes

InChi: InChI=1S/C24H20BrNO5/c1-3-31-22-19(21(27)15-6-4-14(2)5-7-15)12-17(13-20(22)25)23(28)26-18-10-8-16(9-11-18)24(29)30/h4-13H

InChi: InChI=1S/C43H80O22/c1-3-5-7-9-11-13-15-43(16-14-12-10-8-6-4-2

Sacubitril-d4 21718 Epub 2015 Dec 7Sacubitril d4 (AHU 377 d4) is the deuterium labeled Sacubitril. Sacubitril (AHU 377) is a potent NEP inhibitor with an IC50 of 5 nM. Sacubitril (AHU 377) is a component of the heart failure medicine LCZ696. Product information CAS Number: 1884269 07 1 Molecular Weight: 415. 52 Formula: C24H29NO5 Chemical Name: 3 {[(2S,4R) 1 {[1,1' biphenyl] 4 yl} 5 ethoxy 4 methyl 5 oxopentan 2 yl]carbamoyl}(H)propanoic acid Smiles:

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